These effects are typically mild and transient
Le Poole IC, Das PK, van den Wijngaard RM, Bos JD, Westerhof W
Its key to stick to the treatment plan and adjust the dose as needed
For example, a meta-analysis found that two copies of the MTHFR C677T variant (A/A, homozygous) increase the relative risk of heart disease by 38%.[ref][ref] However, not all studies agree, and a large prospective study (n=6,000) found that older people with two copies of the C677T allele were at a 30% decreased risk of death from cardiovascular disease when other parameters were included.[ref] The increased risk is not just due to high homocysteine
Some of the bumps may be slightly red or have an accompanying light-red halo, indicating inflammation
For research around the ankle, Sub-Q is the standard