In December 2020, the FDA also approved Saxenda for weight management in adolescents aged 12-17 who are obese or weigh more than 60 kg (132 pounds) [12]
A 2023 systematic review and meta-analysis of 82 RCTs (10,332 patients) examined probiotics for IBS symptoms, and for abdominal bloating or distension reported only very low certainty in the evidence for a benefit, with some specific combination probiotics and Bacillus strains showing potential signals.[5] Certainty grading reflects how confident the analysis is in the effect estimate
It's important to note that GLP-1 receptor agonists are not indicated for type 1 diabetes or for the treatment of diabetic ketoacidosis (DKA)
PLoS ONE 8 , e72067 (2013)
I look forward to riding roller coasters, wearing dresses without layering and climbing mountains for the first time in my life
Additional research has focused on the relationship between NNMT activity and nicotinamide metabolism, methyl donor utilization, and cellular signaling networks associated with energy balance
