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The Link Between TMAO and MAFLD In recent years, due to the correlation between TMAO and cardiovascular disease (CVD) (Wang et al., 2011) and diabetes (Zhuang et al., 2019), the roles of TMAO in metabolic diseases have attracted extensive attention

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Noteworthy, among them, is the overactivity of the ETC complex, as it has been established that overactivity of ETC is the prominent finding in neurological damage occurring in a diverse set of diseases, as reported from multiple investigations

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This paradoxical response affects some patients receiving hydroxocobalamin treatment for vitamin B12 deficiency

All values were log2 transformed and normalized to the median intensity within each sample