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Additionally, Dula managed to downregulate the inflammatory signaling pathway that involves TGF-1/PI3K/AKT/NF-B levels in the colonic homogenates and raised the expression of TFF-3 and GLP-1, all of which contribute to a better intestinal barrier

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Conversely, administering the medication at night might be preferable for individuals who observe minimal side effects or find that the drug helps mitigate their nighttime cravings