3 In experimental models, hypothyroidism has been shown to lead to a decreased kidney-to body weight ratio, 46,47 truncations in tubular mass, 46,48,49 and various alterations in glomerular architecture (i.e., decreased glomerular basement membrane [GBM] volume and area, GBM thickening, mesangial matrix expansion, increased glomerular capillary permeability)
Free Radical Biol Med 27(56):623635 Corti A, Duarte TL, Giommarelli C, De Tata V, Paolicchi A, Jones GD, Pompella A (2009) Membrane gamma-glutamyltransferaseactivitypromotesiron-dependentoxidative DNA damage in melanoma cells
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Hair plucking on the back of mice induces hair follicles to transition from telogen to anagen [20,21]