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Is synovial macrophage activation the inflammatory link between obesity and osteoarthritis

Normally, eating, especially calorie-dense or highly palatable food, triggers the release of dopamine, a neurotransmitter associated with reward and motivation

The increase in ATP concentration, and thus the increase in the ATP/ADP ratio, closes the potassium channels, decreasing K+ efflux, which causes membrane depolarisation and leads to the opening of calcium channels, allowing extracellular calcium to enter

There are several conditions that can cause burps that smell like sulfur

It activates one receptor (GLP-1) instead of two or three

This means that if youre doing well on a lower dose, theres no need to increase it