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For non-diabetics taking GLP agonists for other reasons most likely reducing body weight the results of this study may not be applicable as the interaction of diabetes-related inflammation, and such may be the reason for such wide-ranging GLP agonist effects. The study authors conclude that their results provide insights into the benefits and risks of GLP-1R and may be useful for informing clinical care and guiding research agendas

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Some peptides may exert anti-inflammatory effects by modulating immune signaling and supporting the action of anti-inflammatory compounds, such as curcumin and omega-3 fatty acids

A few commenters urged CMS to consider the applicability of any well-being or nutrition measures to the outpatient setting, noting that facilities should not be held accountable for factors beyond their control, such as lack of access to healthy foods

You cannot tolerate GI side effects