HPG axis central effects: hypothalamus and pituitary Evidence on the potential neuroendocrine actions of GLP-1 on HPG axis was provided by an in vitro study in a rodent hypothalamic neuronal cell line (GT1-7) that reported a dose-dependent stimulating effect of GLP-1 on GnRH release, in association with a prompt increase in the plasma LH levels following the intracerebroventricular injection of GLP-1 in male rats [34]
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Ayala, J
By studying the animals in metabolic cages that measure metabolic rate, it was further explored that, despite the GLP-1-MK-801-treated mice being significantly smaller in size and consuming less food than the obese control group, they burned the same amount of calories
As the popularity of these medications has soared in recent years, more people have been thinking about how to integrate them into their lives