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Histologically, the structure of the renal tubular architecture was preserved (220)

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Longevity of centenarians is reflected by the gut microbiome with youth-associated signatures

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30 Further work is being carried out to investigate these findings

The analysis of the optimized structures of the MichaelisMenten complex indicate that the polar residues at position 13 (Cys or Ser) stabilize the deprotonated GS , which in turn acts as the catalytic Brnsted base and abstracts the proton at position C2 of substrate 7 (Extended Data Fig