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Despite the robust body of evidence showing the cardiovascular benefits of GLP-1 RAs, their origins as diabetes/glucose medications and the mode of administration of all but one by subcutaneous injection have posed barriers for cardiologists to adopt them as a routine part of clinical practice

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If surgery is performed at the peak of shedding: The apparent size of the problem may be overestimated Donor hair may look temporarily thinner than baseline The risk of temporary shock loss of susceptible native hairs may be higher (especially where miniaturization is already present) A careful clinic will typically prioritize donor safety , conservative density goals, and appropriate staging if needed