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When oxygen delivery improves, many people notice sharper cognition, better memory, and improved motivation

13 Since then, several other GLP-1RAs have undergone clinical trials and have been approved for this use in adults, and they have become increasingly readily available to the public over the last few years

Kurrikoff, K., Vunk, B

Potential direct anti-inflammatory mechanisms from preclinical and early clinical studies include: Modulation of immune cell function : GLP-1 receptor activation may reduce pro-inflammatory cytokine production from macrophages and other immune cells Reduction of oxidative stress : These medications may decrease reactive oxygen species production, which contributes to inflammatory processes Endothelial protection : GLP-1 receptor agonists may improve endothelial function and reduce vascular inflammation Inhibition of inflammatory signalling pathways : Including suppression of nuclear factor-kappa B (NF-B), a key regulator of inflammatory gene expression It's important to note that many of these mechanisms have been primarily demonstrated in laboratory or animal studies, with more limited evidence in humans

This naturally reduces the desire to snack between meals and helps manage portion sizes

The Innovation Medicine 2(3) : 100086