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A drug rash or other reaction may occur for several reasons, such as: an allergic reaction a buildup of the drug that causes toxicity to the skin a drug makes the skin more sensitive to sunlight interaction of two or more drugs In some cases, drug rashes can be idiopathic, meaning theres no known direct cause

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However there is a great variation in the way that different commercial systems prepare and activate the PRP, and hence it is difficult to draw clear conclusions on the efficacy of PRP

or is there a safe area closer to the ankle to administer?