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Building on this potential, to advance the clinical translation of MR, we propose the following key directions: First, achieving precise patient selection-given the heightened sensitivity of MTAP-deficient cancers to MR, MTAP status should be evaluated as a predictive biomarker to prioritize potential beneficiaries

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Investigators noted that ACR20 response was statistically greater than placebo as early as 1 week after the first dose and was sustained through 24 weeks