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In addition to other neuromodulators affected by GLP-1 agonists, Ex-4 increased pro-opiomelanocortin (POMC) expression while decreasing neuropeptide Y (NPY), and this effect was independent of the reduction of food intake and body weight (Yang et al., 2014)

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A case of histopathologically typical toxic epidermal necrolysis despite no visible blisters or erosive lesions