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Researchers dont know precisely why semaglutide and constipation can often go hand-in-hand, but they theorize its related to how the medication works on your digestive system: It slows your digestion: Semaglutide is a glucagon-like peptide-1 receptor ( GLP-1 ) agonist that delays gastric emptying the movement of food from your stomach into your intestines

Additionally, there were no substantial differences observed in the gastric emptying time of liquids, and no significant variation between the gastric emptying times associated with long-acting and short-acting GLP-1 medications

Lukey MJ, Greene KS, Erickson JW, Wilson KF, Cerione RA

Pharmaceutical companies stand to make a lot of money from these drugs

Identification of key pathways, genes and immune cell infiltration in hypoxia of high-altitude acclimatization via meta-analysis and integrated bioinformatics analysis

Quick Answer: Body aches with Wegovy are not listed as common adverse effects in UK prescribing information, but may relate to rapid weight loss, dehydration from gastrointestinal symptoms, nutritional factors, or increased physical activity rather than direct medication effects