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The compound has been used in published research as a tool compound for examining NNMT inhibition effects in cell culture and animal models

Mitophagy, a selective form of autophagy, specifically targets damaged mitochondria for degradation, thereby preventing the release of ROS and subsequent cellular damage

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Both crystallography studies and structural models suggest that IgG binds to FcRn in an upside-down orientation, such that the Fab arms face down towards the membrane in which FcRn is embedded [34, 61]

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PMC6073405 Pickart L, Vasquez-Soltero JM, Margolina A