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Under specific conditions of glucose or amino acid starvation, autophagy is compensatory to participate in the basic metabolic cycle of cells by acting on intracellular proteins, lipids, and other organic macromolecules ( Autophagy in apoptosis Cells can undergo apoptosis in response to intracellular signaling, extracellular signaling, and endoplasmic reticulum (ER) stress ( Figure 4 )

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While weight loss is a common side effect, it is not FDA-approved as a primary weight loss medication

Zhang J et al