Additionally, "GLP-1 medications work differently because they are engineered to stay active much longer, which is why they have a much more powerful and sustained effect on appetite and blood sugar regulation," he said
Rotating the injection site each week can help prevent skin irritation or infections
An imbalance of estrogen and testosterone in women can cause breast tenderness, low sex drive, mood swings, irregular periods, worse PMS symptoms, weight gain, weight loss resistance, hair loss, headaches, endometriosis, polycystic ovarian syndrome (PCOS), and thyroid disorders

When to Call Your Doctor Severe abdominal pain Significant bloating or abdominal swelling Persistent nausea or vomiting Inability to pass gas, which can sometimes be a sign of a blockage in the colon Blood in the stool Black or tarry stools, which may indicate bleeding higher in the digestive tract Pencil-thin stools, which can be a sign of a narrowing or blockage Unexplained weight loss beyond what would be expected from the medication Fever A sudden change in bowel habits A lack of bowel movement for three to seven days, despite making lifestyle changes or taking over-the-counter medications New or worsening constipation after previously doing well on a GLP-1 medication Symptoms that persist for more than a few weeks despite treatment Resources We Trust Cleveland Clinic: Could You Be Pooping Better

If adherence challenges persist despite these strategies, healthcare providers may consider alternative treatment options with different dosing frequencies or delivery methods that better align with individual patient needs and preferences
How to Decide: Discontinuation vs