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The condition is common and physiological in neonates, adolescent boys, and elderly men

doi: 10.1002/jmv.10258 31 DavisHEMcCorkellLVogelJMTopolEJ

In patients with DM2 the incretin response is diminished, but the insulinotropic effect of GLP-1 is conserved.28 Under normal conditions GLP-1 has a short half-life (approximately 2 min), as it is rapidly degraded by dipeptidylpeptidase 4, so GLP-1 analogues resistant to this enzyme have been developed for the treatment of DM2.29 arGLP-1: glucagon-like peptide 1 receptor agonist

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Treatment should be about improving health and quality of life, not about conforming to societal beauty standards or reinforcing harmful weight stigma

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