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The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental

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Compared to natural ligands, retatrutide shows lower potency at GLP-1 and glucagon receptors but higher potency at GIP receptors

Suspected side effects from medicines including those taken as part of a clinical trial can be reported via the MHRA Yellow Card Scheme at yellowcard.mhra.gov.uk or via the Yellow Card app

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Wegovy also contains semaglutide and is used in weight-management contexts