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[14] Lactobacillus paracasei: The Most Directly Studied Strain The 2025 Frontiers in Pharmacology study cited earlier is the most mechanistically sophisticated published research connecting a Lactobacillus strain to TMA reduction

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If nausea arises when GLP-1 RA plasma concentrations are at their peak, then continuous exposure to GLP-1 RAs may lead to tachyphylaxisa reduced response to the drug over timeresulting in fewer gastrointestinal symptoms after long-term use [20]