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The decision to use a combination as initial therapy should be individualized and should be shaped by considerations such as baseline blood pressure, the target goal and the incremental likelihood of achieving goal with a combination compared to monotherapy

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This can be done through oral supplements, B12 injections, or even intravenous therapy for more severe cases

Its best to work with your weight loss provider to determine the right treatment for you

But stress, toxins, poor diet and other lifestyle factors that increase its use will speed up depletion