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The first mention of the molecule in the database stretches back to 1923

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: Off Label Pseudophakic patients with glaucoma (Schmidt et al 2010) A 2010 study (Schmidt et al, 2010) concluded that echothiophate may be effective in lowering IOP in patients with advanced glaucoma that have had previous cataract surgery to replace their eye's natural cloudy lens with a clear aritificial intraocular lens (pseudophakic patients), and for whom maximal medical therapy with newer class medications provides insufficient lowering of IOP

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SUSTAIN-6 showed that semaglutide reduced major adverse cardiovascular events by 26%

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doi: 10.1097/MOG.0b013e3282f323f3 78 ZhaoYChenFWuWSunMBilottaAJYaoSet al

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Its a story of how Japans aversion to drugs, its penchant for shaming people (particularly women) about their weight, and its aversion to individuality have fostered an illegal trade in a medication thats inhaled like oxygen across the world

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