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Retatrutide is not yet available outside clinical trials

10.1016/j.biopha.2018.10.154 87

So if better means fewer side effects , the honest answer is usually: it depends on the person

Examples include acetaminophen (Tylenol) in high doses, certain antifungals, and some cholesterol-lowering medications

Overall, clinical trials showed starting with a lower dose of around 2 mg can reduce the intensity and frequency of GI side effects, compared to a higher initial dose (4 mg)