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Both activate AMPK, but through distinct mechanisms: metformin inhibits complex I of the mitochondrial electron transport chain, raising the cellular AMP:ATP ratio and thereby activating AMPK indirectly
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Lee et al., 2011)
Eligible patients were aged 66 years or older, were diagnosed with diabetes and had a minimum follow-up period of one year post diagnosis
10.1001/jamaneurol.2014.4769 96 RobertX.GouetP
evaluated the precise effects of L-carnitine supplementation on exercise performance, anaerobic power, and exercise-induced oxidative stress
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