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At 100+ pounds of loss, the skin has been dramatically stretched for years and the damage to collagen and elastin networks is more extensive

Vitiligo: Managing and living with this challenging skin condition Reviewed by Megan Noe, MD, MPH, MSCE, Former Editorial Advisory Board Member, Harvard Health Publishing Vitiligo is a chronic condition that affects skin color

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Summary: Vitamin B12 treatment typically begins producing early haematological responses within 34 days, with neurological symptoms starting to improve within 12 weeks, though complete symptom resolution may require several weeks to months depending on deficiency severity and treatment route