In the Phase 3 TRIUMPH-4 trial (68 weeks), retatrutide demonstrated unprecedented weight loss in adults with obesity and knee osteoarthritis, with participants on the highest dose (12 mg) achieving an average weight loss of 28.7% (approximately 71 lbs)
Gradual benefits : Initial improvements (increased energy, better sleep) may appear within weeks
Schellack, G., Harirari, P., & Schellack, N
Instead of taking this approach, the ASA stated, There is no evidence to suggest the optimal duration of fasting for patients on GLP-1 agonists
The reason to stay low is to keep eating during training
Your injury history, training load, surgical timeline (if relevant) and current bloodwork, including inflammatory markers, full blood count, liver and kidney function, and condition-specific tests, are reviewed before any prescription