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GLP-1 therapy represents one of the most significant advancements in modern metabolic medicine

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The GLP-1 receptor activation also reduces appetite and food intake through central nervous system pathways, contributing to significant weight loss observed in clinical trials

These agents include thiazolidinediones (PPAR- agonists), dipeptidyl peptidase-4 (DPP-4) inhibitors, sulfonylureas, sodium-glucose co-transporter 2 (SGLT2) inhibitors, -glucosidase inhibitors, and glucagon-like peptide-1 (GLP-1) receptor agonists

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