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It has also been observed to interact with growth factor pathways, influence extracellular matrix dynamics, and participate in cytoprotective responses under stress conditions
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Future incretin-based therapies Future research in incretin-based treatment of overweight and obesity aims to investigate the potential of combining GLP-1-R agonism with the targeting of other peptide hormones to achieve synergistic effects, with the most prominent targets of interest being the GIPR, the glucagon receptor (GCGR) and the amylin receptor [16]
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