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The answer, for any rational researcher, is zero

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Noticeably, DHA also upregulated a Gpx4 CIRT (Cytoplasmic Intron-sequence Retaining Transcripts), a novel Gpx4 splicing variant, harboring part of the first intronic region, which according to the sentinel RNA hypothesis would expand the ability of Gpx4 (and DHA) to provide neuronal antioxidant defense independently of conventional nuclear splicing in cellular compartments, like dendritic zones, located away from nuclear compartment

Accordingly, in certain embodiments, the subject in need thereof may be a subject identified as being a responder based on: [1] the subject having autism or ASD and having lower plasma and/or intracellular levels of GSH, tGSH, or both, as compared to a control group without a diagnosis of autism or ASD

Shekunova, E