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Materials and methods Primary human hepatocyte isolation Primary human hepatocytes (PHH) were prepared from nontumorous tissues obtained from freshly resected human livers of different donors (PHH Ctrl, n = 4) or explanted livers of WD patients (PHH WD, n = 2) via a two-step perfusion protocol as previously described [8]

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Include vitamin levels (B12, D, iron) to catch any nutritional deficiencies from reduced food intake

159,160 T cells as another type of innate-like T cells exist in the steady-state liver, whose development is sustained in a microbiota-dependent way

Objetivo primario (MACE: muerte CV + infarto no fatal + ictus no fatal): Semaglutida 6,5% vs placebo 8,0% HR 0,80 (IC95% 0,72-0,90

therefore, the anti-inflammatory effects of L-carnitine in fish require further study