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The dosage can be increased by another 2.5mg every 4 weeks to a maximum weekly dose of 15mg

While treatment-emergent HLA antibodies are likely to be reduced by the use of leukocyte-reduced RBCs in both Test and Control arms, we hypothesize that inactivation of residual leukocytes by the amustaline/GSH pathogen reduction process might affect the incidence of alloimmunization

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This is different from intramuscular injections, which go deeper into muscle tissue, or intravenous injections, which go directly into veins

But how likely is that

However, note that the trials had short follow-up and did not evaluate cancer outcomes