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Newer inhibitors should include hydrogen-bond donor or positively ionizable groups that can interact with the Glu205/206 pair in the N-terminal recognition region, as well as hydrophobic components to engage with the S 1 pocket

Interleukin-1 (IL-1) receptor antagonist gene polymorphism in normal weight obese syndrome: relationship to body composition and IL-1 alpha and beta plasma levels

REDEFINE 2 -- CagriSema in T2D (Lingvay et al., 2025): Significant weight loss and glycemic improvement in adults with overweight/obesity and type 2 diabetes

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We all know that L-Carnitine increases use of free fatty acids as the source of muscle energy