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In addition, aggregated Amyloid- activates the p38 mitogen activated protein kinase (MAPK) in cell leading to hyperphosphorylation of protein Tau and formation of neurofibrillary tangles (NFTs) inside neurons, making the microtubules unstable and causing the loss of neuron functionality [80]

doi: 10.1007/s12602-025-10707-y 455 RoySDhaneshwarS

Scand J Med Sci Sports (2013) 23(3):e15061.10.1111/j.1600-0838.2011.01414.x 220 SchlechterNLRussellSMSpencerEMNicollCS

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