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Micronutrient Information Center, Linus Pauling Institute, Oregon State University, Corvallis, OR

[14] There is not enough data to guarantee safety for the fetus or nursing infant

Clinical trials are necessary to determine the appropriate dosage for humans

However, call 999 immediately if you experience signs of anaphylaxis including difficulty breathing, facial swelling, or severe dizziness

Mood-related symptoms of B12 deficiency include persistent irritability, low mood or emotional flatness that doesn't respond to typical coping strategies, restlessness, difficulty concentrating, and a general sense of being "off" that's hard to articulate

General guidelines suggest individuals under 150 pounds may start with 50-75mg daily, those between 150 and 200 pounds typically use 75mg daily as a standard protocol, and individuals over 200 pounds may need 75-100mg daily for optimal effects