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VPA is also a non-competitive inhibitor of high-affinity folate receptors, such as folate receptor (108), and may disturb folic acid metabolism (109)

Eur Heart J 2003;24:442-63.ArticlePubMed 11

At the same time, experts caution that stress alone does not prove a person has a separate leaky gut syndrome, since this is a complex, context-dependent process rather than a single diagnosis

Gilroy CA, Capozzi ME, Varanko AK et al (2020) Sustained release of a GLP-1 and FGF21 dual agonist from an injectable depot protects mice from obesity and hyperglycemia

Mitochondrial and inflammatory biomarkers may also provide clinical context