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10.1111/ajd.13267 220 ShinJ

GLP-1RA/tesaglitazar depends on functional GLP-1R and shows preserved effects in db/db mice When given at a daily dose of 50 nmol kg 1 , 6 days of treatment with GLP-1RA/tesaglitazar robustly improved body weight, fat mass, food intake, blood glucose and glucose tolerance in DIO wildtype mice (Fig

5 Evidence indicates that patients with TED produce autoantibodies that stimulate this receptor complex, causing hyperactivation of orbital fibroblasts and immune cells which mediate the disease process in susceptible individuals

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