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doi: 10.1038/s41586-019-1168-5 210 Alvarez-DominguezJRDonagheyJRasouliNKentyJHRHelmanACharltonJet al

However, if a gland is no longer functioning due to surgical removal or advanced ovarian failure, peptides alone may not be sufficient, and direct hormone replacement may still be necessary

2023:e12840

To najbardziej wymowne porwnanie, bo pochodzi z jednego badania (REDEFINE 1), w ktrym wszystkie trzy ramiona oceniano rwnolegle i pokazuje efekt addytywny dwch szlakw