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The news: Novo Nordisks GLP-1 drug semaglutide failed to slow the progression of Alzheimers disease in new study results, dimming hopes that GLP-1s might be approved to treat the condition

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PLC1, as signal transducer by hydrolyzing membrane lipid to generate second messengers, can promote calcium influx and mtROS production, which triggers the activation of NLRP3 and caspase 1 [12, 125]

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The liver plays a crucial role in insulin metabolism and glycogen synthesis and degradation

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