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The GHK-Cu group showed significantly greater total protein and collagen synthesis demonstrating that the peptide's effects on extracellular matrix accumulation extend to systemic injection, not just topical application

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Compared to corticosteroid injections, peptides do not accelerate tissue degeneration, do not suppress natural healing, and promote long-term improvement rather than temporary relief

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doi: 10.1016/j.clinbiochem.2012.01.016