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Liberal fluid intake is also proposed as a treatment to compensate for the diuretic effect of natriuresis and kaliuresis during keto-induction and its proposed symptoms, however there is no experimental evidence to support this recommendation

Aging Med (Milton) 7, 649667

an effective treatment would be expected to augment striatal synaptic connectivity, protect SN neurons from underlying death inducers, and ideally stimulate the replacement of lost SN neurons from preexisting pools of neural stem cells

There is very little downtime, as most individuals return to their typical daily routine the same day

measured endogenous GLP-1 concentrations

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