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Indeed, the original GSH metabolism constructed by Reed et al
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Interestingly, when growing in proline medium, in which the gdh3/gdh3 mutant cells failed to undergo morphogenesis, they exhibited an overall reduction in extracellular metabolite levels when compared to the wild-type, with the exception of nicotinate, malate, and succinate levels
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Biochemistry (Mosc.) 2000;65:849855
Oral NAC produced a dose-dependent increase in CSF NAC concentrations but did not consistently elevate CSF or brain GSH levels (Katz et al
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