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Short-term pharmacotherapy has not been shown to produce longer-term health benefits and cannot be generally recommended

In animal models, supplementation prevented synaptic damage induced by chronic alcohol, according to a study by Shi Z et al

Its common as you age or if you have a naturally deep-set eye structure

135,148 Clinical studies have shown that sitagliptin, when added to standard-of-care medication, was associated with significant clinical improvement and reduced mortality compared to standard-of-care alone

The primary concerns include additive cardiovascular effects (both can increase heart rate), excessive appetite suppression leading to inadequate nutrition, and potential gastrointestinal side effects