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FDA clarifies policies for compounders as national GLP-1 supply beings to stabilize

And none of the big GLP-1 trials studied anything like microdosing. So right away, if youre going off-label, youre stepping into the unknown. Heres a quick rundown of what might drive someone to try a less-is-more approach: Cost concerns: Depending on your insurance (or lack thereof), these medications can be pricy

Tirzepatide remains the more potent option for several specific populations

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Additionally, experts say those with more severe gastrointestinal diseases, such as gastroparesis and inflammatory bowel disease (IBD), should avoid these medications