These warnings focus on misleading claims, improper prescribing practices, and the sale of products that may not meet FDA-approved standards
The genetic variants, carried by roughly 10% of the general population, cause a surprising and still mysterious phenomenon that researchers refer to as GLP-1 resistance, in which levels of the hormone GLP-1 (glucagon-like peptide-1), which helps regulate blood sugar, are higher but less biologically effective
This combination approach gives patients the best chance of long-term success
Schwarz says the commentary is a call for disciplined use, not a warning against the class of medications
The authors write that there can be self-stigma or internalized stigma, which can lead to reluctance in seeking treatment
In some of the trials, we saw that individuals who had those variants were unable to lower their blood glucose levels as effectively after six months of treatment, said Anna Gloyn, DPhil, professor of pediatrics and of genetics, and one of the studys senior authors
