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GHK-Cu is a potent wound healing agent, promoting angiogenesis, cell proliferation, and the synthesis of growth factors such as vascular endothelial growth factor (VEGF) and fibroblast growth factor-2 (FGF-2)

NLRP3 is expressed in both human and mouse macrophages, dendritic cells, neutrophils and epithelial cells (36)

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Each requires a delivery technology like microinfusion to reach the dermis where fibroblasts live

These application notes consolidate established methodologies from the scientific literature to provide researchers and drug development professionals with robust, reproducible protocols for investigating the cytoprotective mechanisms of this compound in human endothelial systems in vitro