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Others may recommend a more or less rigorous dosing schedule

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Regulation of hepatic glucose metabolism in humans

2.3.3 Nrf2/ARE-GPX4 pathway Current research suggests that Kelch-like ECH-associated protein 1 (Keap1) inhibits the activity of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2), which is a key regulator of oxidative stress