8 While GLP-1 medications are highly effective tools, they are not a cure-all for the chronic condition of obesity
CagriSema and the link between obesity and type 2 diabetes
One study explored mechanistic associations between GLP-1 functioning and mood disorders in humans: a post-mortem investigation showed that, compared with healthy controls, patients who had been diagnosed with mood disorders had lower expression of the gene encoding for GLP-1R in the dorso-lateral prefrontal cortex and the hippocampus, whereas this association was not observed in the brain tissue of people with schizophrenia 176
At Prisk Orthopaedics & Wellness, medically assisted weight management is never a one-size-fits-all prescription
In an interview with Healio | Endocrine Today, Scott Brunner, CAE, CEO of the Alliance for Pharmacy Compounding, an organization that represents more than 600 compounding businesses across the U.S., said many of the safety concerns linked to improper ingredients are not coming from state-licensed compounding pharmacies
Specifically, GLP-1R engagement may alleviate endoplasmic reticulum (ER) stress, suppress microglial overactivation, and attenuate the release of pro-inflammatory cytokines and hippocampal neuronal apoptosis