A study published this month in The Lancet involving about 95,000 people found that among those with diabetes or obesity who also have depression or anxiety, semaglutide (the active ingredient in Novo Nordisks Ozempic and Wegovy) was linked to a lower risk of worsening depression, anxiety, substance use disorder and self-harm - though the results show correlation, not causation
Which medication causes fewer gastrointestinal side effects
Based on the mechanism of action of SNRIs and SSRIs including citalopram, and the potential for serotonin syndrome, caution is advised when citalopram is coadministered with other drugs that may affect the serotonergic neurotransmitter systems, such as triptans, linezolid (an antibiotic which is a reversible non-selective MAOI), lithium, tramadol, or St
406 Wei et al
rather, space them out by at least several hours
Participants who tolerated 15 mg continued on 15 mg as their maximum tolerated dose