While STEP-HFpEF was underpowered to truly detect outcome differences, the difference observed supports the need for larger, outcomes-driven trials in obese patients with HFpEF
This article examines what the current Phase 2 evidence shows, outlines known side effects and safety considerations, and explains the drug's regulatory status in the UK
Spread your protein across 3 to 4 meals per day for optimal absorption, and prioritize high-quality sources like poultry, fish, eggs, dairy, and legumes
Tirzepatide is the first such drug that's made it to market
Based on Phase 2 trial data (Jastreboff et al., NEJM 2023), injection site reactions with retatrutide were among the more commonly reported adverse events, occurring across multiple dose groups
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